A Survey of Visualization and Analysis in High-Resolution Connectomics

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dc.contributor.authorBeyer, Johannaen_US
dc.contributor.authorTroidl, Jakoben_US
dc.contributor.authorBoorboor, Saeeden_US
dc.contributor.authorHadwiger, Markusen_US
dc.contributor.authorKaufman, Arieen_US
dc.contributor.authorPfister, Hanspeteren_US
dc.contributor.editorBruckner, Stefanen_US
dc.contributor.editorTurkay, Cagatayen_US
dc.contributor.editorVrotsou, Katerinaen_US
dc.date.accessioned2022-06-03T05:34:27Z
dc.date.available2022-06-03T05:34:27Z
dc.date.issued2022
dc.description.abstractThe field of connectomics aims to reconstruct the wiring diagram of neurons and synapses to enable new insights into the workings of the brain. Reconstructing and analyzing the neuronal connectivity, however, relies on many individual steps, starting from high-resolution data acquisition to automated segmentation, proofreading, interactive data exploration, and circuit analysis. All of these steps have to handle large and complex datasets and rely on or benefit from integrated visualization methods. In this state-of-the-art report, we describe visualization methods that can be applied throughout the connectomics pipeline, from data acquisition to circuit analysis. We first define the different steps of the pipeline and focus on how visualization is currently integrated into these steps. We also survey open science initiatives in connectomics, including usable open-source tools and publicly available datasets. Finally, we discuss open challenges and possible future directions of this exciting research field.en_US
dc.description.documenttypestar
dc.description.number3
dc.description.sectionheadersA Journey Through Multiple Scales
dc.description.seriesinformationComputer Graphics Forum
dc.description.volume41
dc.identifier.doi10.1111/cgf.14574
dc.identifier.issn1467-8659
dc.identifier.pages573-607
dc.identifier.pages35 pages
dc.identifier.urihttps://doi.org/10.1111/cgf.14574
dc.identifier.urihttps://diglib.eg.org:443/handle/10.1111/cgf14574
dc.publisherThe Eurographics Association and John Wiley & Sons Ltd.en_US
dc.subjectCCS Concepts: Human-centered computing --> Visualization systems and tools; Scientific visualization; Applied computing --> Life and medical sciences; Systems biology
dc.subjectHuman centered computing
dc.subjectVisualization systems and tools
dc.subjectScientific visualization
dc.subjectApplied computing
dc.subjectLife and medical sciences
dc.subjectSystems biology
dc.titleA Survey of Visualization and Analysis in High-Resolution Connectomicsen_US
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