Sequence Tube Maps for Structural Variants
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Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
The Eurographics Association
Abstract
Discovery of large sequence changes-structural variants-is crucial yet challenging in genomics. Pangenome graphs aid in their detection, representing DNA of multiple species as a unified structure. Sequence Tube Maps (STM) visualize these graphs as metro maps but quickly become cluttered. Based on STM, we present SVSTM, which addresses this challenge by reducing visual elements and enabling adjustable detail levels. Overview+detail views highlight large variants, summarize small ones, and offer details on demand. We show SVSTM's utility through use cases and evaluations with domain experts and developers.
Description
CCS Concepts: Human-centered computing → Visual analytics; Applied computing → Genomics
@inproceedings{10.2312:evs.20251091,
booktitle = {EuroVis 2025 - Short Papers},
editor = {El-Assady, Mennatallah and Ottley, Alvitta and Tominski, Christian},
title = {{Sequence Tube Maps for Structural Variants}},
author = {Brandt, Astrid van den and Geelen, Jasper P. J. and Wetering, Huub van de},
year = {2025},
publisher = {The Eurographics Association},
ISBN = {978-3-03868-282-0},
DOI = {10.2312/evs.20251091}
}