Cytosplore Simian Viewer: Visual Exploration for Multi-Species Single-Cell RNA Sequencing Data

Simple item page
dc.contributor.authorBasu, Soumyadeepen_US
dc.contributor.authorEggermont, Jeroenen_US
dc.contributor.authorKroes, Thomasen_US
dc.contributor.authorJorstad, Nikolasen_US
dc.contributor.authorBakken, Trygveen_US
dc.contributor.authorLein, Eden_US
dc.contributor.authorLelieveldt, Boudewijnen_US
dc.contributor.authorHöllt, Thomasen_US
dc.contributor.editorHansen, Christianen_US
dc.contributor.editorProcter, Jamesen_US
dc.contributor.editorRenata G. Raidouen_US
dc.contributor.editorJönsson, Danielen_US
dc.contributor.editorHöllt, Thomasen_US
dc.date.accessioned2023-09-19T11:31:55Z
dc.date.available2023-09-19T11:31:55Z
dc.date.issued2023
dc.description.abstractWith the rapid advances in single-cell sequencing technologies, novel types of studies into the cell-type makeup of the brain have become possible. Biologists often analyze large and complex single-cell transcriptomic datasets to enhance knowledge of the intricate features of cellular and molecular tissue organization. A particular area of interest is the study of whether cell types and their gene regulation are conserved across species during evolution. However, in-depth comparisons across species of such high-dimensional, multi-modal single-cell data pose considerable visualization challenges. This paper introduces Cytosplore Simian Viewer, a visualization system that combines various views and linked interaction methods for comparative analysis of single-cell transcriptomic datasets across multiple species. Cytosplore Simian Viewer enables biologists to help gain insights into the cell type and gene expression differences and similarities among different species, particularly focusing on comparing human data to other species. The system validation in discovery research on real-world datasets demonstrates its utility in visualizing valuable results related to the evolutionary development of the middle temporal gyrus.en_US
dc.description.sectionheadersNeuroanatomy and Omics
dc.description.seriesinformationEurographics Workshop on Visual Computing for Biology and Medicine
dc.identifier.doi10.2312/vcbm.20231219
dc.identifier.isbn978-3-03868-216-5
dc.identifier.issn2070-5786
dc.identifier.pages111-120
dc.identifier.pages10 pages
dc.identifier.urihttps://doi.org/10.2312/vcbm.20231219
dc.identifier.urihttps://diglib.eg.org:443/handle/10.2312/vcbm20231219
dc.publisherThe Eurographics Associationen_US
dc.rightsAttribution 4.0 International License
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCCS Concepts: Human-centered computing -> Visualization systems and tools
dc.subjectHuman centered computing
dc.subjectVisualization systems and tools
dc.titleCytosplore Simian Viewer: Visual Exploration for Multi-Species Single-Cell RNA Sequencing Dataen_US
Files
Original bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
111-120.pdf
Size:
7.01 MB
Format:
Adobe Portable Document Format
Download
No Thumbnail Available
Name:
paper1010_mm.mp4
Size:
65.41 MB
Format:
Unknown data format
Download
Collections
VCBM 2023: Eurographics Workshop on Visual Computing for Biology and Medicine