EuroVisPosters2023
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Browsing EuroVisPosters2023 by Author "Harbig, Theresa"
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Item PTMVision: An Interactive Visualization Platform for Post-Translational Modifications of Proteins(The Eurographics Association, 2023) Hackl, Simon; Jachmann, Caroline; Harbig, Theresa; Witte Paz, Mathias; Nieselt, Kay; Gillmann, Christina; Krone, Michael; Lenti, SimoneIn recent years, proteins have been shown to carry many more post-translational modifications (PTMs) than originally thought. The visualization of proteins along with their PTMs facilitates exploration and understanding of the effects of these PTMs on the protein structure, function, and interactions with other proteins. Therefore, we developed PTMVision, an interactive webbased visualization. We combine information about PTMs in the primary sequence with a two-dimensional representation of the protein's tertiary structure using a presence-absence map and a modified contact map that relates PTMs with the spatial arrangement of proteins without the need of a 3D structure. The prototype of PTMVision is part of the TueVis Visualization Server and is available at https://ptmvision-tuevis.cs.uni-tuebingen.de/.Item Visual Linkage and Interactive Features of Evidente for an Enhanced Analysis of SNP-based Phylogenies(The Eurographics Association, 2023) Witte Paz, Mathias; Harbig, Theresa; Varga, Dolores; Kränzle, Eileen; Nieselt, Kay; Gillmann, Christina; Krone, Michael; Lenti, SimonePhylogenetic trees of a set of bacterial strains are often used to analyze their evolutionary relationships and they are commonly based on genomic features, such as single nucleotide polymorphisms (SNPs). Evidente - a recently published tool - provides visual and analytical linkage across a phylogenetic tree, SNP data and metadata, and integrates them into one interactive visual analytics platform. In contrast to other approaches, Evidente shows how SNPs agree with the tree structure. Evidente is part of the TueVis server (https://evidente-tuevis.cs.uni-tuebingen.de/). Here, we give an overview of the tasks supported by Evidente. The version of Evidente described in the publication can seamlessly visualize up to 150 strains. Thus, we introduce further enhancements for larger trees, such as data-driven aggregation and semantic zooming.