Mlejnek, MatejErmes, PierreVilanova, AnnaRijt, Rob van derBosch, Harrie van denGerritsen, FransGröller, M. EduardBeatriz Sousa Santos and Thomas Ertl and Ken Joy2014-01-312014-01-3120063-905673-31-21727-5296http://dx.doi.org/10.2312/VisSym/EuroVis06/339-346This paper discusses two applications of probing dense volumetric data for MR orthopedics and dynamic contrast enhanced MRI mammography. In order not to reduce the context information and to extract the essential part of the data, we apply Profile Flags. A Profile Flag is a 3D glyph for probing and annotating the volumetric data. The first application area deals with visualization of T2 profiles for interactive inspection of knee cartilage and detection of lesions. In the second application, we present the usability the Profile Flags for measuring of time-signal profiles for a set of time-dependent MR volumes. Several extensions of the basic Profile Flag concept are described in detail and discussed. These extensions include selection of a set of profiles based on spatial as well as curve differences, automatic positioning of the Profile Flags, and adaptation for probing of time-varying volumetric data. Additionally, we include the evaluation of the used methods by our medical partners.Categories and Subject Descriptors (according to ACM CCS): I.3.8 [Computing Methodologies-]: Computer Graphics-Applications; J.3 [Computer Applications-]: Life and medical sciences-Medical information systems